HISTIOCYTOSE X PDF

Definition: Langerhans cell histiocytosis LCH is defined by the association of a clinical and radiological involvement and a biopsy of a pathological tissue. Natural history: the natural history of the disease is very heterogeneous, ranging from auto-regressive lesions to a disease affecting multiple organs with fatal consequences, while some lesions may be responsible for permanent sequels. A multidisciplinary approach: the perception of disease from physicians varies greatly depending on their speciality and experience, as well as the presentation of the disease or the short-term treatment outcomes. But whatever the initial view of the treating physician, a multidisciplinary approach to the LCH is recommended as well as the coordination of the necessary care of this systemic disease and its associated morbidity. Journal page Archives Contents list.

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Definition: Langerhans cell histiocytosis LCH is defined by the association of a clinical and radiological involvement and a biopsy of a pathological tissue. Natural history: the natural history of the disease is very heterogeneous, ranging from auto-regressive lesions to a disease affecting multiple organs with fatal consequences, while some lesions may be responsible for permanent sequels. A multidisciplinary approach: the perception of disease from physicians varies greatly depending on their speciality and experience, as well as the presentation of the disease or the short-term treatment outcomes.

But whatever the initial view of the treating physician, a multidisciplinary approach to the LCH is recommended as well as the coordination of the necessary care of this systemic disease and its associated morbidity. Journal page Archives Contents list. Article Article Outline. Access to the text HTML. Access to the PDF text. Recommend this article.

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Thyroid localization in adult histiocytosis X

Langerhans cell histiocytosis LCH is a rare cancer involving clonal proliferation of Langerhans cells , abnormal cells deriving from bone marrow and capable of migrating from skin to lymph nodes. Symptoms range from isolated bone lesions to multisystem disease. LCH is part of a group of syndromes called histiocytoses , which are characterized by an abnormal proliferation of histiocytes an archaic term for activated dendritic cells and macrophages. These diseases are related to other forms of abnormal proliferation of white blood cells , such as leukemias and lymphomas.

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Langerhans cell histiocytosis

Langerhans cell histiocytosis ex histiocytosis X is usually present in children. Histological aspects are variable. The diagnosis is made in immunolabeling by anti-CD1a. Clinical presentations are variable, depending on their extension. Previous Article Kyste du canal nasopalatin L.

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Langerhans’cell histiocytosis: histiocytosis X, eosinophil granuloma

We'd like to understand how you use our websites in order to improve them. Register your interest. Authors report on a rare case of thyroid involvement by histiocytosis X. A yr- old man with diabetes insipidus and lung bullous disease of 2 yr duration was found to have thyroid gland infiltration by differentiated histiocytosis X. This was based on cytological findings consistent with the diagnosis, obtained by fine needle aspiration biopsy.

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