DEJERINE ROUSSY PDF

The nature of the pain varies considerably between patients, but is often moderate to severe in intensity, can be either persistent or episodic, can be either spontaneous or evoked e. The location of the pain also varies considerably and can affect a large part of the contralateral body or a smaller portion depending on the exact size and location of the thalamic lesion Additionally, the onset of the pain also is extremely variable, with some patients reporting onset immediately, while others years after the stroke Depending on the size and location of the stroke, patients may have other clinical features that are not strictly part of this syndrome or due to thalamic involvement, including 2,4 :.

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The nature of the pain varies considerably between patients, but is often moderate to severe in intensity, can be either persistent or episodic, can be either spontaneous or evoked e. The location of the pain also varies considerably and can affect a large part of the contralateral body or a smaller portion depending on the exact size and location of the thalamic lesion Additionally, the onset of the pain also is extremely variable, with some patients reporting onset immediately, while others years after the stroke Depending on the size and location of the stroke, patients may have other clinical features that are not strictly part of this syndrome or due to thalamic involvement, including 2,4 :.

Furthermore, and partly because of this, this syndrome is considered by many authors to be a diagnosis of exclusion in patients with a known thalamic stroke Furthermore, tumors including metastases , demyelination , and abscesses involving the thalamus can also cause an identical syndrome 5,6. Indeed, multiple studies have cited involvement of the ventroposterior aspect in thalamic lesions as being crucial to the development of this syndrome In particular, one study showed that involvement of the anterior pulvinar nucleus and surrounding nuclei as highly correlating with development of thalamic pain 1.

Although the thalamus is the location of the lesion implicated in this syndrome, central post-stroke pain can also occur due to lesions at any level of the spinothalamic pathway , such as in patients with the lateral medullary syndrome or with cortical lesions 2,7. CT and MRI can demonstrate an infarct or hemorrhage in the thalamus 1. Discussion pertaining to radiographic features of ischemic strokes and hemorrhagic strokes is discussed in more depth elsewhere see individual articles.

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Articles Cases Courses Quiz. About Blog Go ad-free. As of the latest update, Google Chrome and Microsoft Edge have made a breaking change to how file uploads are handled. Once your system installs this update, you will not be able to upload new images. Please use another browser until we can get it fixed. On this page:. Thalamic pain: anatomical and physiological indices of prediction. Central post-stroke pain: clinical characteristics, pathophysiology, and management. Central poststroke pain: an abstruse outcome.

Pubmed 4. Thalamic syndrome: syndrome of the posterior cerebral artery; a review. Dejerine-Roussy syndrome from thalamic metastasis treated with stereotactic radiosurgery. Windows to the Brain. Schmahmann JD, Leifer D. Chronic motor cortex stimulation in patients with thalamic pain. Dejerine J, Roussy G. Le syndrome thalamique. Edit article Share article View revision history Report problem with Article.

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Dejerine–Roussy syndrome

Dejerine—Roussy syndrome or thalamic pain syndrome is a condition developed after a thalamic stroke , a stroke causing damage to the thalamus. Although some treatments exist, they are often expensive, chemically based, invasive, and only treat patients for some time before they need more treatment, called "refractory treatment". Dejerine—Roussy syndrome is most commonly preceded by numbness in the affected side. In these cases, numbness is replaced by burning and tingling sensations, widely varying in degree of severity across all cases. Less commonly, some patients develop severe ongoing pain with little or no stimuli.

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