FARMACOLOGIA DE LOS ANTIPARKINSONIANOS PDF

We report the five known dopaminergic receptors, where they are located, the advantages and disadvantages of the employment in parkinsonian patients. The dopaminergic agonists were introduced to control the limitations of levodopa-increasing the therapheutic window. We analyse the pharmacocynetic efficacy and the side effects of cabergoline, ropinirole and pramipexole. Entretanto, devido a heterogeneidade das metodologias empregadas nos estudos, esses resultados devem ser analisados com reservas 6.

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Los inhibidores de la monoamino oxidasa B se emplean en el tratamiento de esta enfermedad en monoterapia o concomitantemente con levodopa. Los resultados evidenciaron propiedades interesantes del compuesto FCS Rev Neurol Paris. Projected number of people with Parkinson disease in the most populous nations, through Pharmacological treatment of Parkinson disease: A review.

Prog Neurobiol. Emborg M. J Neurosci Methods. Gershanik OS. Improving L-dopa therapy: The development of enzyme inhibitors. Mov Disord. Finberg J. Pharmacol Ther. Life Sci. Synthesis and evaluation of 6-methylphenylcoumarins as potent and selective MAO-B inhibitors. Bioorg Med Chem Lett. A new series of 3-phenylcoumarins as potent and selective MAO-B inhibitors. New halogenated 3-phenylcoumarins as potent and selective MAO-B inhibitors. Focusing on new monoamine oxidase inhibitors: Differently substituted coumarins as an interesting scaffold.

Curr Top Med Chem. Eur J Med Chem. Neuroprotective effect of prenyloxycoumarins from edible vegetables. Neurosci Lett. Neurochem Int. Philippens I. Drug Discov Today Dis Models. Chem Med Chem. ACS Chem Neurosci. Modified coumarins. Synthesis of substituted 5- 4-methoxyphenyl -7H-furo [3,2-g] chromenones. Chem Nat Compd. National Center for Biotechnology Information.

Accessed on: January 20, Different effects of 7-nitroindazole in reserpine-induced hypolocomotion in two strains of mice. Eur J Pharmacol. Ecstasy counteracts catalepsy in rats, an antiparkinsonian effect? Wei L, Chen L. Effects of 5-HT in globus pallidus on haloperidol-induced catalepsy in rats.

Changes in ascorbic acid and malondialdehyde in rats after exposure to mercury. Bratis Lek Listy. Determination of carbonyl content in oxidatively modified proteins. Methods Enzymol. Protein carbonyl levels in serum and gingival crevicular fluid in patients with chronic periodontitis. Arch Oral Biol. Inhibitory effects of cis- and trans-resveratrol on noradrenaline and 5-hydroxytryptamine uptake and on monoamine oxidase activity.

Biochem Biophys Res Commun. Colpaert F. Pharmacological characteristics of tremor, rigidity and hypokinesia induced by reserpine in rats. Kaur S, Starr M. Antiparkinsonian action of dextramethorphan in the reserpine-treated mouse. Pharmacol Exp Ther. MAO-B inhibitors: Multiple roles in the therapy of neurodegenerative disorders? Parkinsonism Relat Disord.

Dual effects of L-3,4-dihydroxyphenylalanine on aromatic L-amino acid decarboxylase, dopamine release and motor stimulation in the reserpine-treated rat: Evidence that behavior is dopamine independent. Effects of clinically relevant doses of methyphenidate on spatial memory, behavioral sensitization and open field habituation: A time related study.

Behav Brain Res. Aged Tg mice are impaired on social memory and open field habituation tests. Duty S, Jenner P. Br J Pharmacol. Involvement of adenosinergic receptor system in an animal model of tardive dyskinesia and associated behavioural, biochemical and neurochemical changes. Possible anti-oxidant and neuroprotective mechanisms of zolpidem in attenuating typical anti-psychotic-induced orofacial dyskinesia -A biochemical and neurochemical study.

Prog Neuropsychopharmacol Biol Psychiatry. Antipsychotic induced oxidative stress in rat brain. Neurotox Res. Quercetin, a bioflavonoid attenuated haloperidol induced orofacial dyskinesia. Possible antioxidant and neuroprotective mechanisms of FK in attenuating haloperidol-induced orofacial dyskinesia. Effects of mitochondrial antioxidant SkQ1 on biochemical and behavioural parameters in a Parkinsonism model in mice. Biochemistry Mosc. Inhibition of rat brain monoamine oxidase activities by psoralen and isopsoralen: Implications for the treatment of affective disorders.

Pharmacol Toxicol. Palabras clave: enfermedad de Parkinson, monoaminooxidasa, cumarinas, modelos animales, reserpina, levodopa, haloperidol, antioxidantes. Olaya, M. Redes sociales.

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